منابع مشابه
Metabolic fuels: regulating fluxes to select mix.
Animals must regulate the fluxes of multiple fuels to support changing metabolic rates that result from variation in physiological circumstances. The aim of fuel selection strategies is to exploit the advantages of individual substrates while minimizing the impact of disadvantages. All exercising mammals share a general pattern of fuel selection: at the same %V(O(2,max)) they oxidize the same r...
متن کاملThe Major Metabolic Fuels
organized work. It is not surprising, therefore, that the active groups of the enzymes should only be capable of acting in association with a carrier of a given structure. For, orderly biological processes are unthinkable without presupposing structure, and it is therefore out of the question that any living constituent of protoplasm could consist of structureless, fluid, independently displace...
متن کاملTranscriptional control of metabolic fluxes
Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden * Corresponding author. Chemical and Biological Engineering, Chalmers University of Technology, Systems Biology, Gothenburg 41128, Sweden. Tel.: þ 46 31 772 3804; Fax: þ 46 31 772 3801; E-mail: [email protected] Molecular Systems Biology 7: 478; published online 29 March 2011; doi:10.1038...
متن کاملPtc7p Dephosphorylates Select Mitochondrial Proteins to Enhance Metabolic Function.
Proper maintenance of mitochondrial activity is essential for metabolic homeostasis. Widespread phosphorylation of mitochondrial proteins may be an important element of this process; yet, little is known about which enzymes control mitochondrial phosphorylation or which phosphosites have functional impact. We investigate these issues by disrupting Ptc7p, a conserved but largely uncharacterized ...
متن کاملUpdate on Metabolic Network Fluxes Inference and Prediction of Metabolic Network Fluxes
In this Update, we cover the basic principles of the estimation and prediction of the rates of the many interconnected biochemical reactions that constitute plant metabolic networks. This includes metabolic flux analysis approaches that utilize the rates or patterns of redistribution of stable isotopes of carbon and other atoms to estimate fluxes, as well as constraints-based optimization appro...
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ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2011
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.047050